Other infections and COVID-19

Other infections and COVID-19

Last updated 2 April 2020

Authors: Dr Pam Collins, Consultant Occupational Physician
Dr Chris Valentine, Consultant Occupational Physician

 

Infection

 

 

Vulnerability

 

 

References

 

Diarrhoea

acute illness

Likely low / return to background once recovery

provided symptoms are not a feature of Covid19

https://academic.oup.com/ecco-jcc/advance-article/doi/10.1093/ecco-jcc/jjaa061/5811674

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(20)30076-5/fulltext

HIV

CD4 count <50

or opportunistic illness in last six months

Very high https://www.tht.org.uk/news/coronavirus-covid-19

https://www.bsg.org.uk/covid-19-advice/

https://www.bhiva.org/BHIVA-and-THT-statement-on-COVID-19-and-advice-for-the-extremely-vulnerable

International AIDS Society Advice

US Dept of Health and Human Services Interim Guidance on COVID-19  for people with HIV

HIV

CD4 count <200, detectable viral load or not on ART

May be high https://www.tht.org.uk/news/coronavirus-covid-19

https://www.bsg.org.uk/covid-19-advice/

https://www.bhiva.org/BHIVA-and-THT-statement-on-COVID-19-and-advice-for-the-extremely-vulnerable

EACS & BHIVA Statement on risk of COVID-19 for people living with HIV (PLWH)

Although people with HIV who are on treatment with a normal CD4 T-cell count and suppressed viral load may not be at an increased risk of serious illness, many people with HIV have other conditions that increase their risk. Indeed, almost half of people living with HIV in Europe are older than 50 years and chronic medical problems such as cardiovascular and chronic lung disease are more common in people living with HIV.

International AIDS Society Advice

US Dept of Health and Human Services Interim Guidance on COVID-19  for people with HIV

HIV

CD4 count ≥ 200 or above and undetectable viral load, on ART

Low https://www.tht.org.uk/news/coronavirus-covid-19

https://www.bsg.org.uk/covid-19-advice/

https://www.bhiva.org/BHIVA-and-THT-statement-on-COVID-19-and-advice-for-the-extremely-vulnerable

EACS & BHIVA Statement on risk of COVID-19 for people living with HIV (PLWH)

Although people with HIV who are on treatment with a normal CD4 T-cell count and suppressed viral load may not be at an increased risk of serious illness, many people with HIV have other conditions that increase their risk. Indeed, almost half of people living with HIV in Europe are older than 50 years and chronic medical problems such as cardiovascular and chronic lung disease are more common in people living with HIV.

International AIDS Society Advice

US Dept of Health and Human Services Interim Guidance on COVID-19  for people with HIV

Respiratory infections

viral, ongoing

Unclear – but will need to follow isolation guidance re risk of having Covid https://www.europeanlung.org/en/QA-covid-19 ( Covid 19 tab)

individuals can get Covid19 in the presence of other URTI – no data on whether the effect will be increased

Respiratory infections

recovered, no other underlying condition

Low – returns to background

No extra restriction once well & after 7 days

https://www.europeanlung.org/en/QA-covid-19 – specific Resp conditions tab

Previous infections do not increase the risk of more severe infections in future unless the previous infections were due to other diseases (such as severe heart or lung conditions, diabetes or conditions or drugs that suppress the immune system)

https://www.pnas.org/content/116/52/27142  – some indication of possible short lived viral ‘protection’ after infection with another URTI

Sepsis Returns to low once fully recovered.

Increased restriction period likely -duration dependent upon severity of previous sepsis

https://sepsistrust.org/uk-sepsis-trust-announcement-regarding-coronavirus

Evidence suggests that, for a period of time following sepsis, some survivors can be more prone to developing further infections, and therefore have an increased risk of readmission with infective complications (including sepsis). These people may be at increased risk of severe illness if they acquire CoViD-19.

If, since your illness with sepsis, you have been well and not experienced repeated infections or problems with your immunity then the impact of a CoViD-19 infection is likely to be same the same of the majority of the population – in other words, a relatively mild illness.

TB

pulmonary

Increased https://www.europeanlung.org/en/QA-covid-19 – specific Resp conditions tab

post-TB lung damage often puts you at a higher risk of picking up chest infections and so you might be at slightly higher risk of having a chest infection if you were infected with COVID-19

RELATED CONTENT

Vulnerability levels

Very high (Red)

Risk of severe illness or death if contracts COVID-19. Read more

High (Orange)

Likely to need hospitalisation if contracts COVID-19, with protracted illness and heavy NHS burden. Read more

Increased/Moderate (Yellow)

Increased risk compared with healthy individual but should recover.

Low/Standard (Green)

No greater risk than healthy individual.